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Source

Mouse

Applications

IHC

Reactivity

Human,Rat,Mouse

Dilution

IHC 1:50-200

Storage

-20°C/1 year

Specificity

TBP/TATA Binding Protein protein detects endogenous levels of TBP/TATA Binding Protein

Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen

Recombinant Protein of TBP/TATA Binding Protein

Uniprot No

P20226

Alternative names

TBP/TATA Binding Protein

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Background

TATA-box binding protein(TBP) Homo sapiens Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin

Concentration

1 mg/ml